Basic Information
VIS ID
TVIS44021366
Fusion event
HTLV-1-ABHD12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
25355254/25374618 (Hg38)
End
25355254/25374618 (Hg38)
Orient
-
Location type
Intronic
Target gene
ABHD12
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-484 ; hsa-mir-423-3p ; hsa-mir-769-3p ; hsa-mir-450b-3p ; hsa-mir-638 ; hsa-mir-4713-3p ; hsa-mir-661 ; hsa-mir-6778-3p ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-6836-5p ; hsa-mir-6132 ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-1205 ; hsa-mir-4485-5p ; hsa-let-7a-2-3p ; hsa-let-7g-3p ; hsa-mir-1247-3p ; hsa-mir-302a-5p ; hsa-mir-3177-5p ; hsa-mir-320a ; hsa-mir-320b ; hsa-mir-320c ; hsa-mir-320d ; hsa-mir-4264 ; hsa-mir-4429 ; hsa-mir-4521 ; hsa-mir-4532 ; hsa-mir-4706 ; hsa-mir-4753-5p ; hsa-mir-488-3p ; hsa-mir-519a-3p ; hsa-mir-519b-3p ; hsa-mir-519c-3p ; hsa-mir-552-3p ; hsa-mir-5681a ; hsa-mir-5692a ; hsa-mir-622 ; hsa-mir-6730-5p ; hsa-mir-6800-5p ; hsa-mir-6802-5p ; hsa-mir-6825-5p ; hsa-mir-7106-5p ; hsa-mir-766-5p ; hsa-mir-9-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/6903927; hsa-mir-1-1/Downstream/833568;
Nearest TSS
ENST00000382410/Upstream/34869; ENST00000473460/Downstream/15516;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/125852, chr20-CpG: 141/Downstream/15081
Upstream sequence
atttcgctcttgttgcccaggctggagtgcagtggcacgatctcagctcactgcaacctccgcctcccaggttcaagtgattctcctgcctcagcctccc
Downstream sequence
gagtagctgggattacaggcatgtgccaccacacccggctaattttgtaattttagtagagacaggacacagggtttctccatgttggtcaggctggtct
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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