Basic Information
VIS ID
TVIS44021378
Fusion event
HTLV-1-ZNF341 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
32338465/33750659 (Hg38)
End
32338465/33750659 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZNF341
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/1512812; hsa-mir-1-1/Downstream/298460;
Nearest TSS
ENST00000382410/Upstream/18649; ENST00000493497/Downstream/36429;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/17911, chr20-CpG: 30/Downstream/40372
Upstream sequence
ctcaagcaatcctccctgctcagcctcctgaggagctgggactacatacatggtgccaacatacttggctaattttaaaaaaaaatttttttttttttga
Downstream sequence
gatggagtctcgctcttgtcacctaggctggagtgcagtggcaccatctcggctcactgcaatctccgcatcctgggttcaagcgattctcctgtctcag
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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