Basic Information
VIS ID
TVIS44021379
Fusion event
HTLV-1-MAP1LC3A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
33140269/34552465 (Hg38)
End
33140269/34552465 (Hg38)
Orient
+
Location type
Intronic
Target gene
MAP1LC3A
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/86047; hsa-mir-1-1/Downstream/437911;
Nearest TSS
ENST00000382410/Upstream/5611; ENST00000360668/Downstream/5643;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/35727, chr20-CpG: 101/Downstream/5866
Upstream sequence
ttgaacgctttcataatgaaatgcccagaaaaATTATACAGCATATTggaaggcctccctgaggagacacttgaaccaaaactcgaggtgagggtgtgag
Downstream sequence
ggacacagagatcccggggaaggatgttccaggcaaaggccctggggcatgagcctgacagggattcctagagtagccaggaggccagaggagtagcggg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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