Basic Information
VIS ID
TVIS44021381
Fusion event
HTLV-1-FER1L4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
34152920/35565004 (Hg38)
End
34152920/35565004 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
FER1L4
Nearest miRNA
hsa-mir-103a-2/Upstream/110907; hsa-mir-1-1/Downstream/2951559;
Nearest TSS
ENST00000382410/Upstream/8394; ENST00000462896/Downstream/50888;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/22715, chr20-CpG: 140/Downstream/35793
Nearest cancer related gene
FER1L4(TSG, No orient, 0)
Upstream sequence
TTAGCTCCAGGATCCTGGCAAGGAGGGAGAGGGACTGAGGTCACTTCCATGCTCCAGGAGGTGGTCTGGGGAGGAGGCGGGTGTGTCAGCATCCCCTGTC
Downstream sequence
CATTCCCTTGCCATTCCTAGGCCAGCTGCCACAAGGCCACAGGGCTGGATGCTCCTGCAGCTACCCCGTTTCCACCCCACAGGGCCCAGCCTCACTCTCC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate