VISDB Viral Integration Site DataBase

VIS ID

TVIS44021383

Fusion event

HTLV-1-BLCAP integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr20

Cytoband

q11.23

Reference genome

Start

End

36146651/37518249 (Hg38)

Orient

-

Location type

UTR3

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-138-5p ; hsa-mir-130b-3p ; hsa-mir-218-5p ; hsa-mir-19b-3p ; hsa-mir-1301-3p ; hsa-mir-548aw ; hsa-mir-431-5p ; hsa-mir-146b-3p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-1233-3p ; hsa-mir-1225-3p ; hsa-mir-432-5p ; hsa-mir-5699-3p ; hsa-mir-6779-3p ; hsa-mir-4421 ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-10a-3p ; hsa-mir-3662 ; hsa-mir-1252-3p ; hsa-mir-302c-3p ; hsa-mir-520c-3p ; hsa-mir-373-3p ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-520d-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-520e ; hsa-mir-302d-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-130a-3p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-19a-3p ; hsa-mir-339-5p ; hsa-mir-6810-5p ; hsa-mir-4652-5p ; hsa-mir-3191-3p ; hsa-mir-3144-5p ; hsa-mir-1199-3p ; hsa-mir-3194-5p ; hsa-mir-6809-5p ; hsa-mir-2467-5p ; hsa-mir-93-3p ; hsa-mir-6893-3p ; hsa-mir-370-3p ; hsa-mir-6830-5p ; hsa-mir-596 ; hsa-mir-651-3p ; hsa-mir-4520-2-3p ; hsa-mir-4520-3p ; hsa-mir-100-3p ; hsa-mir-125a-3p ; hsa-mir-1276 ; hsa-mir-4726-3p ; hsa-mir-500b-3p ; hsa-mir-6807-5p

Nearest miRNA

hsa-mir-103a-2/Upstream/2064152; hsa-mir-1-1/Downstream/998314;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/111449, chr20-CpG: 120/Downstream/1952

Nearest cancer related gene

BLCAP(TSG, No orient, 0)

Upstream sequence

CCCCTCCTTGGGACAGTTGAGAAAGGCAGGAGGAAGGGCAAAGGAAGTGAGGCTGGGCGGGAAAGCTTGAGCCCAGACACCCAGGTGAAAGAGCAACATC

Downstream sequence

TATCTGTTGCTTCCTTTCTTAAAAATGAAGTGGAGAAAATACTGAAGATTTGTGGACAACTAACAGTCAAGACATGTTTCTGTCTAGCCTGCTGAACAAG