VISDB Viral Integration Site DataBase

VIS ID

TVIS44021388

Fusion event

HTLV-1-PLCG1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr20

Cytoband

q12

Reference genome

Start

End

39792638/41163998 (Hg38)

Orient

-

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-34a-5p ; hsa-mir-1914-3p ; hsa-mir-744-3p ; hsa-mir-92a-3p ; hsa-mir-3616-5p ; hsa-mir-573 ; hsa-mir-6894-5p ; hsa-mir-516b-5p ; hsa-mir-765 ; hsa-mir-7154-3p ; hsa-mir-766-5p ; hsa-mir-4795-5p ; hsa-mir-4635 ; hsa-mir-6885-3p ; hsa-mir-4693-3p ; hsa-mir-302d-5p ; hsa-mir-302b-5p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-552-5p ; hsa-mir-302c-5p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-8084 ; hsa-mir-3143 ; hsa-mir-5692a ; hsa-mir-369-3p ; hsa-mir-200b-3p ; hsa-mir-429 ; hsa-mir-200c-3p ; hsa-mir-6777-5p ; hsa-mir-335-3p ; hsa-mir-670-3p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-1298-5p ; hsa-mir-6832-3p ; hsa-mir-6866-3p ; hsa-mir-188-5p ; hsa-mir-483-3p ; hsa-mir-665 ; hsa-mir-103a-2-5p ; hsa-mir-155-3p ; hsa-mir-217 ; hsa-mir-298 ; hsa-mir-3158-5p ; hsa-mir-3180-5p ; hsa-mir-3685 ; hsa-mir-384 ; hsa-mir-4418 ; hsa-mir-509-3-5p ; hsa-mir-509-5p ; hsa-mir-520a-5p ; hsa-mir-525-5p ; hsa-mir-6807-3p

Nearest miRNA

hsa-mir-103a-2/Upstream/2647366; hsa-mir-1-1/Downstream/5025;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/25806, chr20-CpG: 121/Downstream/152956

Upstream sequence

CTGCCTCTCCTTGCCTATCCAGGTACCTGACCGGGGACCAGTTCTCCAGTGAGTCCTCCTTGGAAGCCTATGCTCGCTGCCTGCGGATGGGCTGTCGCTG

Downstream sequence

CATTGAGTGTGCGTGGGGTCCAGGGCTGGGGGAGGGAAGATGGGAGGCCTGCCCGCTTGACCATGGTGATGTTGCTCCCCAGTGGACTGCTGGGACGGCC