VISDB Viral Integration Site DataBase

VIS ID

TVIS44021391

Fusion event

HTLV-1-JPH2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr20

Cytoband

q13.12

Reference genome

Start

End

42772262/44143622 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-24-3p ; hsa-mir-3180-5p ; hsa-mir-4309 ; hsa-mir-3198 ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-4294 ; hsa-mir-1289 ; hsa-mir-4534 ; hsa-mir-8082 ; hsa-mir-488-5p ; hsa-mir-6514-5p ; hsa-mir-6730-3p ; hsa-mir-1273h-3p ; hsa-mir-4771 ; hsa-mir-3166 ; hsa-mir-17-3p ; hsa-mir-1205 ; hsa-mir-1184 ; hsa-mir-3158-5p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-6829-3p ; hsa-mir-8485 ; hsa-mir-6791-3p ; hsa-mir-6747-3p ; hsa-mir-5193 ; hsa-mir-3941 ; hsa-mir-603 ; hsa-mir-640 ; hsa-mir-6513-3p ; hsa-mir-8079 ; hsa-mir-1245a ; hsa-mir-4789-3p ; hsa-mir-8057 ; hsa-mir-6805-3p ; hsa-mir-5691 ; hsa-mir-7641 ; hsa-mir-143-5p ; hsa-mir-6879-3p ; hsa-mir-5698 ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-4284 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-3194-3p ; hsa-mir-6499-3p ; hsa-mir-6773-3p ; hsa-mir-5693 ; hsa-mir-500b-3p

Nearest miRNA

hsa-mir-103a-2/Upstream/2974544; hsa-mir-1-1/Downstream/264498;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/27239, chr20-CpG: 122/Downstream/15954

Upstream sequence

tgctgcagatactgaggtctgagctggatccagtccccgtggtctgcagtgatgcctcaataacacacacctgcaatgcctgtccttcttccttctcgtg

Downstream sequence

ctccccgctcacgccctctcagctcctccctcctggcatcacctaccagtaaactatctgcacctgaatccttgtctcaggctctgcttttgcaggaacc