Basic Information
VIS ID
TVIS44021392
Fusion event
HTLV-1-KCNK15 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
43379365/44750724 (Hg38)
End
43379365/44750724 (Hg38)
Orient
-
Location type
Exonic
Target gene
KCNK15
Nearest miRNA
hsa-mir-103a-2/Upstream/342521; hsa-mir-1-1/Downstream/674786;
Nearest TSS
ENST00000382410/Upstream/4703; ENST00000445830/Downstream/59547;
Nearest CpG islands
chr20-CpG: 73/Target, None/Upstream, None/Downstream
Upstream sequence
CCCCAgcccgcgccccccgggggcgcccgAGAGCCGTGGCCTCTGGCTGCCCCGCCGCCCGGCCCGCTCCGTGGGCTCCGCCTCTGTCTTCTGCCACGTG
Downstream sequence
CACAAGCTGGAGAGGTGCGCCCGCGACAACCTGGGCTTTTCGCCCCCCTCGAGCCCGGGGGTCGTGCGTGGCGGGCAGGCTCCCAGGCTTGGGGCCCGGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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