Basic Information
VIS ID
TVIS44021405
Fusion event
HTLV-1-chr20 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.31
Reference genome
GRCh37/hg19
Start
55535113/56960057 (Hg38)
End
55535113/56960057 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-103a-2/Upstream/2891572; hsa-mir-1-1/Downstream/361445;
Nearest TSS
ENST00000382410/Upstream/229660; ENST00000442780/Downstream/145684;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/34011, chr20-CpG: 26/Downstream/132014
Nearby gene
BMP7(-208696) ;
Nearest cancer related gene
BMP7(OG, -208696) ;
Upstream sequence
ccaaagagggttgtaccgattcgtcctctcactgaggacatttgagagtgcctgctaaccgcccccttgctgacagggATCAAAGCCATCAGGAAGAGCC
Downstream sequence
CTCCGAAGAACAGAATGAGTTGAATGTGTCAGAGAAAAGAGGTGATCCCACGTTTCACTCAACGGGGCTCTTAGGTCATTTGTTTGCACTTTGCTTTTAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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