VISDB Viral Integration Site DataBase

VIS ID

TVIS44021415

Fusion event

HTLV-1-NTSR1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr20

Cytoband

q13.33

Reference genome

Start

End

61345483/62714131 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-26b-5p ; hsa-mir-1185-5p ; hsa-mir-1249-5p ; hsa-mir-1262 ; hsa-mir-1273h-5p ; hsa-mir-1285-3p ; hsa-mir-1321 ; hsa-mir-149-3p ; hsa-mir-2392 ; hsa-mir-30b-3p ; hsa-mir-3187-5p ; hsa-mir-3605-5p ; hsa-mir-3679-5p ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-378g ; hsa-mir-4419a ; hsa-mir-4486 ; hsa-mir-4505 ; hsa-mir-4510 ; hsa-mir-4701-3p ; hsa-mir-4710 ; hsa-mir-4728-5p ; hsa-mir-4731-5p ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-4779 ; hsa-mir-485-5p ; hsa-mir-5189-5p ; hsa-mir-5787 ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-612 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-615-5p ; hsa-mir-661 ; hsa-mir-6735-3p ; hsa-mir-6736-5p ; hsa-mir-6742-3p ; hsa-mir-6776-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6785-5p ; hsa-mir-6797-5p ; hsa-mir-6799-5p ; hsa-mir-6825-5p ; hsa-mir-6860 ; hsa-mir-6871-5p ; hsa-mir-6878-3p ; hsa-mir-6883-5p ; hsa-mir-6884-5p ; hsa-mir-7106-5p ; hsa-mir-7155-5p ; hsa-mir-765 ; hsa-mir-7704

Nearest miRNA

hsa-mir-1-1/Upstream/149118; hsa-mir-124-3/Downstream/464369;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/4263, chr20-CpG: 22/Downstream/57824

Upstream sequence

ggaggttgcagtgagccaagatcacaccactgcactccagcctgggtgacaactgtctcaaagaaaaaaaaaGTTGCAGAAGAAGTTCTTCAAGGGGTCC

Downstream sequence

TTAGGAACAGCCTGCTCCACTCTGACCTCCCGTGAGGACGGGAAGGGGACCCACGCCACGCAGCTGTGGGCAGCTCTGGCTCTGGCCGTAGCGGCCACAG