Basic Information
VIS ID
TVIS44021426
Fusion event
HTLV-1-BAGE integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
11097803/10414652 (Hg38)
End
11097803/10414652 (Hg38)
Orient
+
Location type
Intronic
Target gene
BAGE
Nearest miRNA
hsa-mir-10396a/Upstream/1426987; hsa-let-7c/Downstream/2991732;
Nearest TSS
ENST00000624081/Upstream/71915; ENST00000612957/Downstream/106901;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/8914, chr21-CpG: 159/Downstream/106391
Upstream sequence
TGGGTGGCTGGGGCCAGTTTCAGCGAAGGCACTCACACCCACCCTCCAAAGTCCAGCCTCTCCTCCTAGACCAAGCTGGCCTCCTGACCTGGGGTGGGGA
Downstream sequence
CTGGAGACACCACAGTGTCCGAGGCTAGTTGGGGAGCAAGAACAGCAGAAACTCAGACCCAGCCAGTCCTCCCCACCCAAGTACCAGTTCCCATTCCTGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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