Basic Information
VIS ID
TVIS44021428
Fusion event
HTLV-1-ABCC13 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
15652866/14280545 (Hg38)
End
15652866/14280545 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
ABCC13
Nearest miRNA
hsa-mir-10396a/Upstream/556271; hsa-let-7c/Downstream/2258544;
Nearest TSS
ENST00000624081/Upstream/56170; ENST00000449214/Downstream/102642;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/63958, chr21-CpG: 50/Downstream/102505
Upstream sequence
GCTTTATGCCCCTTGCTCTGCAGTTCACAGAAACAAAACTGCTCAATTTTATCTACAGATATGTTCCCAAGAGTGGATTAATCTTTTAAAAAATGATTAG
Downstream sequence
GTACTAGATACCCCAAACTCAAATAGTCTTTAAAAatgcagagataaatgagttagtttctgtcttctaggaattcatagtagaattaaaaagattaaaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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