Basic Information
VIS ID
TVIS44021438
Fusion event
HTLV-1-chr21 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
21201851/19829537 (Hg38)
End
21201851/19829537 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7c/Upstream/1143373; hsa-mir-155/Downstream/3249747;
Nearest TSS
ENST00000624081/Upstream/527924; ENST00000486367/Downstream/70218;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/1583980, chr21-CpG: 89/Downstream/1167568
Nearby gene
LINC00320(-913057) ;
Upstream sequence
TATTTTTGTCTTTTTTTTTTTTGCTTAATTTGATAAATCTTGTCGTTGAGGGAAGAAAATATCTTTTAAGGGTGGGGACTTAATATTTTTTCTGAAGAGC
Downstream sequence
TTATATATTTTAAAGTACCACATTTCTGACATGTAAACATCAGAGCTGCATAGAACTTATTTTCTCACATTTGAAAAGGGATAGCCCTCTTAAGAGGTAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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