Basic Information
VIS ID
TVIS44021445
Fusion event
HTLV-1-chr21 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
27158804/25786493 (Hg38)
End
27158804/25786493 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7c/Upstream/212449; hsa-mir-3197/Downstream/1167468;
Nearest TSS
ENST00000624081/Upstream/50820; ENST00000455275/Downstream/111490;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/50593, chr21-CpG: 127/Downstream/383082
Nearby gene
GABPA(+14033) ;
Upstream sequence
gataaatcttatttgagtccatagacaagtcttgataaatttaaaaggattaaaaccacacaaagtatgttctctgactataagggatttaattagaaat
Downstream sequence
caatagcagaaagatacgtagagaatacccaatgatttggaaattaaacaatacattAAAAAGAATttttttactatatacatttaaagctgtgcatttc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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