Basic Information
VIS ID
TVIS44021452
Fusion event
HTLV-1-LINC00945 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.11
Reference genome
GRCh37/hg19
Start
34430372/33058066 (Hg38)
End
34430372/33058066 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LINC00945
Nearest miRNA
hsa-let-7c/Upstream/2682688; hsa-mir-3197/Downstream/492596;
Nearest TSS
ENST00000624081/Upstream/237; ENST00000426947/Downstream/12078;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/23836, chr21-CpG: 206/Downstream/11834
Upstream sequence
GGAGAACCCATCTGCAGTACAGTGCTGGGGGAGGCCAGGGAAGGAGGCTGGGTGTGAACATCCAAAGAGCCTGCAGAGTGGGCACAATATGGGCTGTCGC
Downstream sequence
CAGCTCACGATGCCTCCCTTTCTCTGGGCTGCAGTCGGCATCTACGATTAATAAGACATAGAGAAGTCATTCACCAGAAGTCCTCTTAGAAAAAGCAGTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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