VISDB Viral Integration Site DataBase

VIS ID

TVIS44021460

Fusion event

HTLV-1-KCNJ6 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr21

Cytoband

q22.13

Reference genome

Start

End

39243424/37871121 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-148b-3p ; hsa-mir-128-3p ; hsa-mir-3157-5p ; hsa-mir-6503-3p ; hsa-mir-3116 ; hsa-mir-1254 ; hsa-mir-422a ; hsa-mir-378i ; hsa-mir-378h ; hsa-mir-378f ; hsa-mir-378e ; hsa-mir-378d ; hsa-mir-378c ; hsa-mir-378b ; hsa-mir-378a-3p ; hsa-mir-645 ; hsa-mir-3690 ; hsa-mir-3910 ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-7702 ; hsa-mir-493-5p ; hsa-mir-584-5p ; hsa-mir-151a-3p ; hsa-mir-758-5p ; hsa-mir-218-2-3p ; hsa-mir-5580-3p ; hsa-mir-8076 ; hsa-mir-6867-5p ; hsa-mir-574-5p ; hsa-mir-210-3p ; hsa-mir-297 ; hsa-mir-567 ; hsa-mir-511-3p ; hsa-mir-7850-5p ; hsa-mir-5004-3p ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-130b-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6756-3p ; hsa-mir-6868-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-4469 ; hsa-mir-6734-3p ; hsa-mir-5088-3p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-4698 ; hsa-mir-2276-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-6741-3p ; hsa-mir-4532 ; hsa-mir-1247-3p ; hsa-mir-6890-3p ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-6516-5p ; hsa-mir-3678-3p ; hsa-mir-1273h-3p ; hsa-mir-3667-3p ; hsa-mir-129-5p ; hsa-mir-4284 ; hsa-mir-1304-3p ; hsa-mir-122-3p ; hsa-mir-4279 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-885-3p ; hsa-mir-8088 ; hsa-mir-5196-3p ; hsa-mir-4725-5p ; hsa-mir-6719-3p ; hsa-mir-502-3p ; hsa-mir-501-3p ; hsa-mir-888-3p ; hsa-mir-3148 ; hsa-mir-3675-3p ; hsa-mir-216b-5p ; hsa-mir-651-3p ; hsa-mir-548c-3p

Nearest miRNA

hsa-let-7c/Upstream/2150313; hsa-mir-3197/Downstream/1575889;

Nearest TSS

Nearest CpG islands

None/Target, chr21-CpG: 261/Upstream/195495, chr21-CpG: 107/Downstream/44522

Upstream sequence

CTTTCCTGATTCTTCTCTCCCATTCATTACCTTTTTTTTTCCTATTTTCATTCCCTCCTCTTGATGTTGAGGGCTCCACTGACTGCCATTGACACAAGAG

Downstream sequence

CTTAGTATGGATGGAGGGGACAGTTTCAAGTGGATGAGAACTATCATGGCAAATGACAGGATAGTTGGATTGGGCACACCTTGCATCCTGTACCGTGGGG