VISDB Viral Integration Site DataBase

VIS ID

TVIS44021471

Fusion event

HTLV-1-TRAPPC10 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr21

Cytoband

q22.3

Reference genome

Start

End

45453614/44033733 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-186-5p ; hsa-mir-330-5p ; hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-mir-193b-3p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-4713-5p ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-4762-5p ; hsa-mir-4753-3p ; hsa-mir-130b-5p ; hsa-let-7a-5p ; hsa-let-7b-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-1233-5p ; hsa-mir-1249-5p ; hsa-mir-1294 ; hsa-mir-1321 ; hsa-mir-149-3p ; hsa-mir-202-3p ; hsa-mir-3921 ; hsa-mir-4278 ; hsa-mir-4316 ; hsa-mir-4419a ; hsa-mir-4458 ; hsa-mir-4468 ; hsa-mir-4500 ; hsa-mir-4510 ; hsa-mir-4653-5p ; hsa-mir-4682 ; hsa-mir-4685-5p ; hsa-mir-4716-3p ; hsa-mir-4723-5p ; hsa-mir-4728-5p ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-503-5p ; hsa-mir-5088-5p ; hsa-mir-5698 ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-6732-5p ; hsa-mir-6785-5p ; hsa-mir-6794-5p ; hsa-mir-6797-5p ; hsa-mir-6805-5p ; hsa-mir-6825-5p ; hsa-mir-6837-5p ; hsa-mir-6870-5p ; hsa-mir-6883-5p ; hsa-mir-7111-5p ; hsa-mir-760 ; hsa-mir-98-5p

Nearest miRNA

hsa-let-7c/Upstream/423744; hsa-mir-6815/Downstream/1444533;

Nearest TSS

Nearest CpG islands

None/Target, chr21-CpG: 261/Upstream/20636, chr21-CpG: 103/Downstream/73342

Upstream sequence

gaggatcgcttgagcctaggagttcaagaccggcctgagcaacatagtgaaacccctgtctctgtaaagaagaaataaaattagctggacatggtggtgc

Downstream sequence

acgcctgtagtcctagccacttgggaggctgaggtgagaggatcacttgagcccaggagttggaggctacagtgagctgagattgcaccactgcactcca