Basic Information
VIS ID
TVIS44021492
Fusion event
HTLV-1-IGL integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
22426901/22072490 (Hg38)
End
22426901/22072490 (Hg38)
Orient
+
Location type
Intronic
Target gene
IGL
Nearest miRNA
hsa-mir-1286/Upstream/419105; hsa-let-7a-3/Downstream/750286;
Nearest TSS
ENST00000624155/Upstream/2265; ENST00000518581/Downstream/2876;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/89554, chr22-CpG: 79/Downstream/42221
Nearby gene
TOP3B(-89661) ;
Upstream sequence
ATCTCTCCCTGCTGGTCAATTGCCCTGCAGGGGCTTTTCTTATTTCTCCATTATGAGAATTCCTTTGTTTTTGGAGGAAATAATTTTTATCTAATTTTTG
Downstream sequence
ATTTACTTATCATAATCCTAGAATTTGTATAAAAACTCCTGTTTTTGCATAATGAAACAGTTGCTATCTCATGCCATTTTATTCAAAGTCATGTGCTTCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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