Basic Information
VIS ID
TVIS44021503
Fusion event
HTLV-1-chr22 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
28209362/27813374 (Hg38)
End
28209362/27813374 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1286/Upstream/1258051; hsa-let-7a-3/Downstream/107151;
Nearest TSS
ENST00000624155/Upstream/11876; ENST00000485599/Downstream/47241;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/10770, chr22-CpG: 108/Downstream/105226
Nearby gene
MN1(-11876) ;
Nearest cancer related gene
MN1(OG, -11876) ;
Upstream sequence
ctgcctgggctcaagtgattctcctgcctcagcctcccaagtagctgggattacaggcacctgccaccacatccagctaatttttgtatttttagtagag
Downstream sequence
acggggttttgccatgttggccacactggtctcaaattcctgacctcaggtgatctgcccgccttggcctcccaaagtgctgggattataagcgtgagcc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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