Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene27549939279780142867986528075134280764222811219828113302281116132811174228114902
Basic Information
VIS ID
TVIS44021504
Fusion event
HTLV-1-TTC28 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
28510890/28114902 (Hg38)
End
28510890/28114902 (Hg38)
Orient
-
Location type
Intronic
Target gene
TTC28
miRNAs that regulate target gene
hsa-mir-378a-3p ; hsa-mir-182-5p ; hsa-mir-6741-5p ; hsa-mir-6514-3p ; hsa-mir-7977 ; hsa-mir-4727-3p ; hsa-mir-6866-5p ; hsa-mir-6748-5p ; hsa-mir-877-5p ; hsa-mir-550a-5p ; hsa-mir-550a-3-5p ; hsa-mir-6811-3p ; hsa-mir-1271-3p ; hsa-mir-214-5p ; hsa-mir-5690 ; hsa-mir-20b-3p ; hsa-mir-5588-3p ; hsa-mir-1296-3p ; hsa-mir-374c-3p ; hsa-mir-548s ; hsa-mir-3926 ; hsa-mir-3190-5p ; hsa-mir-6849-3p ; hsa-mir-3675-3p ; hsa-mir-6771-3p ; hsa-mir-548c-3p ; hsa-mir-4786-5p ; hsa-mir-129-5p ; hsa-mir-3688-3p ; hsa-mir-4496 ; hsa-mir-5093 ; hsa-mir-651-3p ; hsa-mir-6885-3p
Nearest miRNA
hsa-mir-1286/Upstream/194290; hsa-let-7a-3/Downstream/344967;
Nearest TSS
ENST00000624155/Upstream/20767; ENST00000485599/Downstream/191743;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/194932, chr22-CpG: 109/Downstream/564210
Upstream sequence
ctcaaactcttgggctcaagttatcttcctgccttggcctcctaaagcactgggattgcaggggtaagccaacatgtcaggccAATACAGATATTTTTAA
Downstream sequence
ATGCAGGTAATTCCAAAAATATGTATCATTTGACTTCAGCTAAAAGCAACTTCCTGATAGGTAAGCTTTTCTTGAGAACCTCTCTGTGCCTGGCTCGCTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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