VISDB Viral Integration Site DataBase

VIS ID

TVIS44021515

Fusion event

HTLV-1-TOB2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr22

Cytoband

q13.2

Reference genome

Start

End

41842708/41446704 (Hg38)

Orient

-

Location type

UTR5

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-378a-3p ; hsa-mir-302a-3p ; hsa-mir-122-5p ; hsa-mir-877-5p ; hsa-mir-744-5p ; hsa-mir-106b-3p ; hsa-mir-320a ; hsa-mir-221-3p ; hsa-mir-630 ; hsa-mir-766-5p ; hsa-mir-3173-3p ; hsa-mir-6891-5p ; hsa-mir-4732-5p ; hsa-mir-3611 ; hsa-mir-7106-5p ; hsa-mir-765 ; hsa-mir-6081 ; hsa-mir-3202 ; hsa-mir-574-5p ; hsa-mir-7515 ; hsa-mir-1252-5p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-4433b-3p ; hsa-mir-6876-5p ; hsa-mir-4476 ; hsa-mir-6510-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-7844-5p ; hsa-mir-4777-5p ; hsa-mir-526a ; hsa-mir-523-5p ; hsa-mir-522-5p ; hsa-mir-520c-5p ; hsa-mir-519c-5p ; hsa-mir-519b-5p ; hsa-mir-519a-5p ; hsa-mir-518f-5p ; hsa-mir-518e-5p ; hsa-mir-518d-5p ; hsa-mir-6770-5p ; hsa-mir-1253 ; hsa-mir-548ax ; hsa-mir-548ao-5p ; hsa-mir-8067 ; hsa-mir-5586-3p ; hsa-mir-6508-5p ; hsa-mir-6127 ; hsa-mir-5006-5p ; hsa-mir-6748-5p ; hsa-mir-6742-5p ; hsa-mir-92a-2-5p ; hsa-mir-4483 ; hsa-mir-6766-5p ; hsa-mir-1293 ; hsa-mir-6756-5p ; hsa-mir-6745 ; hsa-mir-363-5p ; hsa-mir-6747-5p ; hsa-mir-608 ; hsa-mir-4651 ; hsa-mir-4664-5p ; hsa-mir-342-5p ; hsa-mir-504-3p ; hsa-mir-4745-5p ; hsa-mir-4755-3p ; hsa-mir-4481 ; hsa-mir-6813-5p ; hsa-mir-6085 ; hsa-mir-3941 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-1207-5p ; hsa-mir-125a-3p ; hsa-mir-3934-5p ; hsa-mir-4493 ; hsa-mir-4736 ; hsa-mir-4740-3p ; hsa-mir-4763-3p ; hsa-mir-506-5p ; hsa-mir-6815-5p ; hsa-mir-6865-5p ; hsa-mir-7150 ; hsa-mir-7160-3p ; hsa-mir-764 ; hsa-mir-892c-5p

Nearest miRNA

hsa-mir-1281/Upstream/193654; hsa-let-7a-3/Downstream/454240;

Nearest TSS

Nearest CpG islands

chr22-CpG: 177/Target, None/Upstream, None/Downstream

Upstream sequence

GGGGCCCGAGGGCGGGCGGGCGGACTAGCGGCGACGACGCGGGGATGGCGGATCGGAGGGTGGTTCGTGTCGCGCAACGGCAGACGGTATGGGCTGTCGC

Downstream sequence

CGGCAGACGGTCCTGCCCTCCTGGCCCCGCGTCGCCCGAGCCACGGCTTGCCTCAGCCAACAACCCGCACCTTCCCGCGCCCCGGCCCGAAGTGAGCAAA