VISDB Viral Integration Site DataBase

VIS ID

TVIS44021516

Fusion event

HTLV-1-CENPM integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr22

Cytoband

q13.2

Reference genome

Start

End

42342435/41946431 (Hg38)

Orient

-

Location type

Exonic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-106b-5p ; hsa-mir-5698 ; hsa-mir-744-3p ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-143-5p ; hsa-mir-3652 ; hsa-mir-4430 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6499-3p ; hsa-mir-367-5p ; hsa-mir-8088 ; hsa-mir-1267 ; hsa-mir-216b-5p ; hsa-mir-216a-5p ; hsa-mir-498 ; hsa-mir-29b-2-5p ; hsa-mir-6836-3p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-29b-1-5p ; hsa-mir-4772-3p ; hsa-mir-1304-3p ; hsa-mir-660-3p ; hsa-mir-6890-3p ; hsa-mir-665 ; hsa-mir-6771-5p ; hsa-mir-7160-5p ; hsa-mir-423-3p ; hsa-mir-4722-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-6787-3p ; hsa-mir-6746-5p ; hsa-mir-1207-3p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-34b-3p ; hsa-mir-23c ; hsa-mir-23b-3p ; hsa-mir-23a-3p ; hsa-mir-130a-5p ; hsa-mir-4468 ; hsa-mir-4792 ; hsa-mir-6891-3p ; hsa-mir-136-5p ; hsa-mir-6072 ; hsa-mir-150-5p ; hsa-mir-3199 ; hsa-mir-365a-5p ; hsa-mir-365b-5p ; hsa-mir-4722-3p ; hsa-mir-6727-3p ; hsa-mir-6747-3p ; hsa-mir-8052

Nearest miRNA

hsa-mir-1281/Upstream/23134; hsa-let-7a-3/Downstream/3254523;

Nearest TSS

Nearest CpG islands

chr22-CpG: 71/Target, None/Upstream, None/Downstream

Upstream sequence

GCTGGGCTTCGGAGTTTAGCAGCTAGGACCGAATCCCTCTGGAGTGAGAGACACGTGGGCCCAGGCCACAGCCGCGGCTACTTACACCTTCAGCTCGGAG

Downstream sequence

GCGCAGTCCTCTTTGAGCATCGAGTCCGCCAGCTGCTGCAGAAGAGCATCCTCCGTGCCCACCAGCTGCGCAGGGAGAGAGAGCGGACAGTCGAGCCCTA