Basic Information
VIS ID
TVIS44021523
Fusion event
HTLV-1-chr22 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.31
Reference genome
GRCh37/hg19
Start
46515280/46119400 (Hg38)
End
46515280/46119400 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA22A
Nearest miRNA
hsa-let-7a-3/Upstream/5632; hsa-mir-12114/Downstream/2154964;
Nearest TSS
ENST00000624155/Upstream/33397; ENST00000460086/Downstream/31121;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/33256, chr22-CpG: 23/Downstream/3174
Nearby gene
MIRLET7BHG(+5472) ;
Upstream sequence
GAGCCTGTCAGAGCATTCGGGGTGCCGGGTGGGGAGGGATGGCTGGTCCCCGAGTGAAGAAGGCCAAGCTGTGTCCACAGAGGTCATGGTGAGCCCAGGA
Downstream sequence
GTCCAGGAAGGGCCCAGCCAGGTTGTCCACCGCCCCTGCCAGGCCAGAGGAGTTGAGGCTTTGGGTAGCACCCCGCAGGCCCAGCAGTAGAGCTCATATG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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