Basic Information
VIS ID
TVIS44021532
Fusion event
HTLV-1-chr22 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.32
Reference genome
GRCh37/hg19
Start
48536696/48140879 (Hg38)
End
48536696/48140879 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA22A
Nearest miRNA
hsa-let-7a-3/Upstream/2027111; hsa-mir-12114/Downstream/133485;
Nearest TSS
ENST00000624155/Upstream/88233; ENST00000446364/Downstream/122;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/927307, chr22-CpG: 25/Downstream/68466
Nearby gene
MIR3201(+133480) ;
Upstream sequence
TTGGggatccaggacccagatctgctgctccgcagttgtgtgaccttgggaaggtcaGGTCCCACCCTGGGTGTGCTCTTCTTTCCTGAAGATTCAATCC
Downstream sequence
GGCCTGTGTGCTAGGAGTGGAGGGCCTGCTGGAGTCTGAGGAAGATGGCAGCTGGGTCGGTAGCAGGGTGAGCAGGGTCTGAGTGGGGCCAGGCTTCCCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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