Basic Information
VIS ID
TVIS44021538
Fusion event
HTLV-1-chrX integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
100671569/101416581 (Hg38)
End
100671569/101416581 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7f-2/Upstream/6353355; hsa-mir-105-1/Downstream/5223233;
Nearest TSS
ENST00000429181/Upstream/8286; ENST00000453574/Downstream/1706;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/8268, chrX-CpG: 39/Downstream/1622
Nearby gene
RPL36A-HNRNPH2(-2441) ; ARMCX4(+1682) ;
Upstream sequence
gccttggcctctcaaagtgctgggattacaggtgtgaacctctgtccagccaataagctgtgttttaacaagtgctcagggtggttctgctgcaGGAAAC
Downstream sequence
TACTGGCTGATGGATACATGGATTCCATTATCCACCCATTCATTGATTCCTGCATTCACTCATCCAACCCTAAAGGAGGTAACCAAAACAGAGACAATCC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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