Basic Information
VIS ID
TVIS44021552
Fusion event
HTLV-1-WDR44 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q24
Reference genome
GRCh37/hg19
Start
117562700/118428737 (Hg38)
End
117562700/118428737 (Hg38)
Orient
+
Location type
Intronic
Target gene
WDR44
miRNAs that regulate target gene
hsa-mir-192-5p
Nearest miRNA
hsa-let-7f-2/Upstream/42266; hsa-mir-105-1/Downstream/1218001;
Nearest TSS
ENST00000429181/Upstream/35989; ENST00000633080/Downstream/67161;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/82212, chrX-CpG: 17/Downstream/66430
Upstream sequence
gtgtggcaattcctcaaagacctagaaccagaaataccatttgacccagcaatcccattactgggtatatacccaaaggaatagaaatcattgtgttata
Downstream sequence
aagatacatgcaggcatatgttcattgcagcactattccatatagcaaagacattgaatcaacaaaaatgcctatcaatgatagactgggtaaagaaaat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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