Basic Information
VIS ID
TVIS44021585
Fusion event
HTLV-1-LOC105373151 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
28003036/27984919 (Hg38)
End
28003036/27984919 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105373151
Nearest miRNA
hsa-mir-23c/Upstream/7967732; hsa-let-7f-2/Downstream/510636;
Nearest TSS
ENST00000429181/Upstream/3470; ENST00000302196/Downstream/601476;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/120864, chrX-CpG: 30/Downstream/2262136
Nearby gene
DCAF8L1(-3470) ;
Upstream sequence
GATTACTTTTCACTTTTGTGAGTTAGTGTACAATACTGGTAGAATTGAGAAAAGTAGGTCATTGACCACGTCCAGATGGGCAAAGATATTTAGCTTGTGG
Downstream sequence
AGAAGTAGGCCAATCGCACCACAATGAAGACATCTGCCTGCTTAATTACTGCTGCATTAAACGATAACCTTCACATTTTCTTCTAGCTCTACTGTCACTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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