Basic Information
VIS ID
TVIS44021605
Fusion event
HTLV-1-MSN integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q12
Reference genome
End
64935634/65715772 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-200c-3p ; hsa-mir-133a-3p ; hsa-mir-124-3p ; hsa-mir-215-5p ; hsa-mir-615-3p ; hsa-let-7b-5p ; hsa-mir-200b-3p ; hsa-mir-6746-5p ; hsa-mir-30b-3p ; hsa-mir-6772-3p ; hsa-mir-3691-5p ; hsa-mir-3165 ; hsa-mir-3689d ; hsa-mir-6851-5p ; hsa-mir-4448 ; hsa-mir-4268 ; hsa-mir-6134 ; hsa-mir-4524a-3p ; hsa-mir-6770-5p ; hsa-mir-92a-2-5p ; hsa-mir-6748-5p ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-6745 ; hsa-mir-363-5p ; hsa-mir-6846-5p ; hsa-mir-6848-5p ; hsa-mir-4697-5p ; hsa-mir-4488 ; hsa-mir-1237-5p ; hsa-mir-4489 ; hsa-mir-4795-5p ; hsa-mir-664b-5p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-7113-5p ; hsa-mir-9500 ; hsa-mir-6824-5p ; hsa-mir-4536-5p ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-3175 ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-5591-5p ; hsa-mir-4300 ; hsa-mir-6731-5p ; hsa-mir-8085 ; hsa-mir-6500-5p ; hsa-mir-4633-3p ; hsa-mir-6783-5p ; hsa-mir-4779 ; hsa-mir-122-5p ; hsa-mir-1226-5p ; hsa-mir-1321 ; hsa-mir-144-3p ; hsa-mir-1914-3p ; hsa-mir-2467-5p ; hsa-mir-3126-5p ; hsa-mir-3144-5p ; hsa-mir-3148 ; hsa-mir-3151-5p ; hsa-mir-3191-3p ; hsa-mir-338-3p ; hsa-mir-4419a ; hsa-mir-4424 ; hsa-mir-4433b-3p ; hsa-mir-4435 ; hsa-mir-4447 ; hsa-mir-4472 ; hsa-mir-4510 ; hsa-mir-4530 ; hsa-mir-4534 ; hsa-mir-4652-5p ; hsa-mir-4716-3p ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-5194 ; hsa-mir-574-5p ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-615-5p ; hsa-mir-625-5p ; hsa-mir-651-3p ; hsa-mir-6734-5p ; hsa-mir-6738-5p ; hsa-mir-6742-5p ; hsa-mir-6794-5p ; hsa-mir-6796-5p ; hsa-mir-6798-5p ; hsa-mir-6800-5p ; hsa-mir-6802-5p ; hsa-mir-6810-5p ; hsa-mir-6822-3p ; hsa-mir-6830-5p ; hsa-mir-6834-5p ; hsa-mir-6875-5p ; hsa-mir-7106-5p ; hsa-mir-765 ; hsa-mir-766-3p ; hsa-mir-8065 ; hsa-mir-2115-5p ; hsa-mir-3185 ; hsa-mir-345-3p ; hsa-mir-4725-5p
Nearest miRNA
hsa-let-7f-2/Upstream/1929685; hsa-mir-105-1/Downstream/303098;
Upstream sequence
tttgtacactgagactttgctgaagttatttatcagattaaggagcttttgggccgagactattggattttctagatataggatcatgtcatctgcaaac
Downstream sequence
aaggatagtttgacttcctctcctcttgcttggttgccctctatttctttctctggtctgattgctctggccaggacttctaatactatgttgaatatga
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate