Basic Information
VIS ID
TVIS44021627
Fusion event
HTLV-1-DUX4L19 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrY
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
13488931/11333255 (Hg38)
End
13488931/11333255 (Hg38)
Orient
-
Location type
Intronic
Target gene
DUX4L19
Nearest miRNA
hsa-mir-3690-2/Upstream/6727027; hsa-mir-12120/Downstream/2145922;
Nearest TSS
ENST00000430575/Upstream/1422457; ENST00000417071/Downstream/1329079;
Nearest CpG islands
chrY-CpG: 104/Target, None/Upstream, None/Downstream
Upstream sequence
AGCCTGCCGGTTGCTTGCGCGGTGGGACAGCCTGGGCCCGCTCAAGCGGGGCCACAGGGCCAAGGTGTGCTTGCGCCACCCGCGTCCCAGGGGAGTCCGT
Downstream sequence
GTTGGGGCTGGGGCAGGGGTTCCCAGGGCCCAGGGGCGGCCTGGGAACCCCAAGCCAGGGTAGCTCCACCTCGCCAGCCCATGCCCCTGGAGGCCTCTGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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