Basic Information
VIS ID
TVIS44021632
Fusion event
HTLV-1-BCORP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrY
Cytoband
q11.222
Reference genome
GRCh37/hg19
Start
21628568/19466682 (Hg38)
End
21628568/19466682 (Hg38)
Orient
+
Location type
ncRNA_exonic
Target gene
BCORP1
Nearest miRNA
hsa-mir-12120/Upstream/5987416;
Nearest TSS
ENST00000430575/Upstream/389266; ENST00000465253/Downstream/227924;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/388563, chrY-CpG: 41/Downstream/35913
Upstream sequence
AGCTTCATGGACTGGGAAGCTGGTAGCAACTCTTGCAAGCAGTTGAAGGGCTTCATCTCCTGCTTGGATGAAGTCAGATCATAGTTGGAACTGGGTTCAA
Downstream sequence
GTTGCTTTCTGAATCTTGGGACAGTTGACTAAGACAAAACGAATTAGTATACACAGTTAAGATTAAGACTACATCCTTTCCACATCCACTGCTTCCCCTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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