Basic Information
VIS ID
TVIS44021633
Fusion event
HTLV-1-chrY integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrY
Cytoband
q11.223
Reference genome
GRCh37/hg19
Start
22215678/20053792 (Hg38)
End
22215678/20053792 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12120/Upstream/6574526;
Nearest TSS
ENST00000430575/Upstream/308853; ENST00000465253/Downstream/464615;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/486122, chrY-CpG: 16/Downstream/522147
Nearby gene
KDM5D(-308853) ;
Upstream sequence
AACACTGGAAATACGAAGACACCAGGAAAGCATAATACCCTATTTTCAAGAGTTGATGACCTGAATCCCTGTGTAGCTCTCTAATGCAAAGATGAGAGTC
Downstream sequence
ACAGCAACTGGGTCAAATAATAAATTTTGAAGAAAATGAAGACTGTGTTCTCAGTTCCAGGTGCTTCATCAGGCTCATTGTGGATCCAGACTACCAGACA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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