VISDB Viral Integration Site DataBase

VIS ID

TVIS44021656

Fusion event

HTLV-1-AGTRAP integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr1

Cytoband

p36.22

Reference genome

Start

End

11809823/11749766 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-125a-5p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-155-5p ; hsa-mir-377-5p ; hsa-mir-766-3p ; hsa-mir-940 ; hsa-mir-3681-3p ; hsa-mir-6086 ; hsa-mir-6512-3p ; hsa-mir-6720-5p ; hsa-mir-6733-3p ; hsa-mir-6808-5p ; hsa-mir-6893-5p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-3942-3p ; hsa-mir-3915 ; hsa-mir-5100 ; hsa-mir-1294 ; hsa-mir-7160-5p ; hsa-mir-655-5p ; hsa-mir-1827 ; hsa-mir-3928-3p ; hsa-mir-4649-3p ; hsa-mir-1250-3p ; hsa-mir-1245b-3p ; hsa-mir-5582-5p ; hsa-mir-6749-3p ; hsa-mir-6069 ; hsa-mir-4469 ; hsa-mir-532-3p ; hsa-mir-8073 ; hsa-mir-221-5p ; hsa-mir-660-3p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-662 ; hsa-mir-664a-5p ; hsa-mir-4794 ; hsa-mir-5195-3p ; hsa-mir-145-5p ; hsa-mir-6820-5p ; hsa-mir-4660 ; hsa-mir-6849-3p ; hsa-mir-6736-3p ; hsa-mir-3614-3p ; hsa-mir-7108-5p ; hsa-mir-6818-3p ; hsa-mir-6873-3p ; hsa-mir-663b ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-874-5p ; hsa-mir-7110-3p ; hsa-mir-6845-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-199b-5p ; hsa-mir-199a-5p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7977 ; hsa-mir-513b-5p ; hsa-mir-3165 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-4736 ; hsa-mir-3665 ; hsa-mir-6089 ; hsa-mir-383-3p ; hsa-mir-125b-2-3p ; hsa-mir-4457 ; hsa-mir-624-3p ; hsa-mir-3974 ; hsa-mir-340-3p ; hsa-mir-3613-3p ; hsa-mir-371a-5p ; hsa-mir-371b-5p ; hsa-mir-372-5p ; hsa-mir-373-5p ; hsa-mir-4668-5p ; hsa-mir-616-5p ; hsa-mir-6827-3p

Nearest miRNA

hsa-mir-12136/Upstream/1782308; hsa-mir-101-1/Downstream/279392;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/13560, chr1-CpG: 25/Downstream/12316

Upstream sequence

GCCCGGGGCTGATGTCCCTCTGCCCAGGTTCCTAAGCACGTGCTGCCTGGGGAAGCCCatggcacaggggccaggagcctggctttggactcggctgcct

Downstream sequence

aggcgtgggtcccagcatcatcagctttgagctgtgtgatctcgggcaagtcacttcatccctttgacccacagtctcctcatctgtaaagtggggacaa