Basic Information
VIS ID
TVIS44021667
Fusion event
HTLV-1-NBPF25P integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
148913978/143439009 (Hg38)
End
148913978/143439009 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA1F
Target gene
NBPF25P
Nearest miRNA
hsa-mir-101-1/Upstream/26344281; hsa-mir-1182/Downstream/2411578;
Nearest TSS
ENST00000473358/Upstream/21858485; ENST00000443018/Downstream/61503;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/84346, chr1-CpG: 17/Downstream/10323
Upstream sequence
gttgactgtccttgctgtggcactgtgcACCGTCGGTGGGGAGAACACTCCTGGTCCTTAGGAATCCATTTCTAAAGGACATCAGGAGCACAAACAAGTT
Downstream sequence
CATGCCCTATTGTTCTTTCCACGTAAAAGAAGTTGATGACATTTATGCTTTTCTCACAATACACCATTAAGATAGAACATTGTTGAATTATTTGTGGATT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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