Basic Information
VIS ID
TVIS44021678
Fusion event
HTLV-1-PMF1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q22
Reference genome
GRCh37/hg19
Start
156185000/156215209 (Hg38)
End
156185000/156215209 (Hg38)
Orient
-
Location type
Intronic
Target gene
PMF1
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-26b-5p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-101-1/Upstream/263873; hsa-mir-1182/Downstream/205132;
Nearest TSS
ENST00000473358/Upstream/2183; ENST00000471413/Downstream/26753;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1903, chr1-CpG: 44/Downstream/1237
Upstream sequence
aagcgatccactcacctctgcctcccaaagtgctgggattacaggcatgagccactgcacccaggcggaaccacctttttgaagaattacagaacgaatg
Downstream sequence
tataggaaaaggggacagcctgtgcaaagtccctgaggtgatcagatattccaggaactggcagagaccttcttggctacagcatagtgatcagagtaaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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