Basic Information
VIS ID
TVIS44021697
Fusion event
HTLV-1-QSOX1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q25.2
Reference genome
End
180156323/180187188 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-let-7e-5p ; hsa-mir-5096 ; hsa-mir-6803-5p ; hsa-mir-6751-5p ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-197-3p ; hsa-mir-6832-5p ; hsa-mir-193b-5p ; hsa-mir-7110-5p ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-6835-5p ; hsa-mir-3926 ; hsa-mir-1273f ; hsa-mir-4716-5p ; hsa-mir-4781-3p ; hsa-mir-320e ; hsa-mir-6807-5p ; hsa-mir-6778-3p ; hsa-mir-150-5p ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-3159 ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-3156-3p ; hsa-mir-711 ; hsa-mir-6859-3p ; hsa-mir-532-3p ; hsa-mir-4301 ; hsa-mir-3150b-3p ; hsa-mir-3174 ; hsa-mir-4323 ; hsa-mir-4530 ; hsa-mir-4689 ; hsa-mir-4784 ; hsa-mir-646 ; hsa-mir-6858-5p ; hsa-mir-921 ; hsa-mir-106a-3p ; hsa-mir-122-5p ; hsa-mir-1286 ; hsa-mir-130a-3p ; hsa-mir-130b-3p ; hsa-mir-1825 ; hsa-mir-1827 ; hsa-mir-199a-5p ; hsa-mir-199b-5p ; hsa-mir-2467-5p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-3135b ; hsa-mir-3188 ; hsa-mir-3652 ; hsa-mir-3666 ; hsa-mir-3671 ; hsa-mir-3925-3p ; hsa-mir-3975 ; hsa-mir-4295 ; hsa-mir-4430 ; hsa-mir-4499 ; hsa-mir-454-3p ; hsa-mir-4634 ; hsa-mir-4649-3p ; hsa-mir-4695-3p ; hsa-mir-4722-5p ; hsa-mir-4768-3p ; hsa-mir-485-5p ; hsa-mir-504-3p ; hsa-mir-580-3p ; hsa-mir-607 ; hsa-mir-652-3p ; hsa-mir-6736-3p ; hsa-mir-6787-3p ; hsa-mir-6808-5p ; hsa-mir-6857-3p ; hsa-mir-6884-5p ; hsa-mir-6893-5p ; hsa-mir-8083 ; hsa-mir-873-3p ; hsa-mir-940
Nearest miRNA
hsa-mir-101-1/Upstream/383163; hsa-mir-1182/Downstream/251126;
Upstream sequence
CTGGGGCTGCCCTCGGGTGATTTGTGCCTCTCCTTGGGAACTTCCTGCCAGCCTGATCCCTCCTTCCCACCTCCCTGTCCTGGCCCCCTGGCTTGGTCAC
Downstream sequence
ATGAATGCGTGGTGACACTGAGAGGGCCTGACAGGGACATTTCAGCCTAAGGCAGGACAGTCGTTGGCCCCTCACTGAAGTCCCATGCAAAATGAGCCCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate