Basic Information
VIS ID
TVIS44021701
Fusion event
HTLV-1-LOC105371657 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
189481399/189512269 (Hg38)
End
189481399/189512269 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1K
Target gene
LOC105371657
Nearest miRNA
hsa-mir-101-1/Upstream/9073879; hsa-mir-1182/Downstream/3204059;
Nearest TSS
ENST00000473358/Upstream/606581; ENST00000419614/Downstream/263196;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/2831320, chr1-CpG: 56/Downstream/3296233
Upstream sequence
CAGGAACTTTATTAAGTGAAGGGATGGGGTGGCAGTGGTAGAGTGGATGACTATTTGCTTCTGACAGGGTGCCTGTTTATGtattatacaaaataatatt
Downstream sequence
gaatatatattattaaGAAATCTGTTAAAAATTAAGTAAAACTCAGATTCATGTTCTTAAAAGGCACAACATTTGCTATGGCAACAAGATAAAAAATGTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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