VISDB Viral Integration Site DataBase

VIS ID

TVIS44021704

Fusion event

HTLV-1-CAPZB integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr1

Cytoband

p36.13

Reference genome

Start

End

19804067/19477573 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-130b-3p ; hsa-mir-34a-5p ; hsa-mir-1915-5p ; hsa-mir-484 ; hsa-mir-324-3p ; hsa-mir-3934-5p ; hsa-mir-218-5p ; hsa-mir-6885-5p ; hsa-mir-328-5p ; hsa-mir-4745-3p ; hsa-mir-1538 ; hsa-mir-766-5p ; hsa-mir-7-5p ; hsa-mir-483-5p ; hsa-mir-887-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-1273f ; hsa-mir-4518 ; hsa-mir-1266-5p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-211-3p ; hsa-mir-1322 ; hsa-mir-6760-5p ; hsa-mir-185-5p ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-652-3p ; hsa-mir-147b ; hsa-mir-25-3p ; hsa-mir-3202 ; hsa-mir-32-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-4325 ; hsa-mir-4468 ; hsa-mir-4747-5p ; hsa-mir-5196-5p ; hsa-mir-548ad-3p ; hsa-mir-5694 ; hsa-mir-6081 ; hsa-mir-661 ; hsa-mir-6807-5p ; hsa-mir-7515 ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-9500 ; hsa-mir-101-3p ; hsa-mir-1285-3p ; hsa-mir-196a-3p ; hsa-mir-3187-5p ; hsa-mir-5189-5p ; hsa-mir-582-5p ; hsa-mir-612 ; hsa-mir-6860 ; hsa-mir-939-3p

Nearest miRNA

hsa-mir-12136/Upstream/580425; hsa-mir-101-1/Downstream/1156106;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/138791, chr1-CpG: 84/Downstream/7636

Upstream sequence

AAGACTTTTCACACCAGAAGGATGTGGTGGATTAAGGCTCCTCCTTCCAGTTTCTGAGCACAAAACTGCAACGCAGGGAGCCCACTCATGTGAAACCAAC

Downstream sequence

GACAGCCCATCAGGGTCAAAGCCTCACGACGGAGAAGCCTTCAGCAGCAACACTCTACCTGCCAATCACTGCTGCAACTGAGAAGGGAAAAGGGCACCGG