VISDB Viral Integration Site DataBase

VIS ID

TVIS44021714

Fusion event

HTLV-1-PLEKHA6 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr1

Cytoband

q32.1

Reference genome

Start

End

204327326/204358198 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-412-3p ; hsa-mir-136-5p ; hsa-mir-377-3p ; hsa-mir-485-5p ; hsa-mir-190a-3p ; hsa-mir-1277-5p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-3074-3p ; hsa-mir-410-3p ; hsa-mir-5011-5p ; hsa-mir-8066 ; hsa-mir-574-5p ; hsa-mir-1279 ; hsa-mir-487a-3p ; hsa-mir-154-3p ; hsa-mir-2054 ; hsa-mir-6081 ; hsa-mir-3166 ; hsa-mir-4468 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-5699-5p ; hsa-mir-3121-3p ; hsa-mir-455-5p ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-mir-6888-3p ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-3605-5p ; hsa-mir-3679-5p ; hsa-mir-1185-5p ; hsa-mir-7162-3p ; hsa-mir-4649-3p ; hsa-mir-130b-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6818-3p ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-3120-5p ; hsa-mir-6728-3p ; hsa-mir-4653-5p ; hsa-mir-3921 ; hsa-mir-4714-5p ; hsa-mir-4290 ; hsa-mir-18a-3p ; hsa-mir-1324 ; hsa-mir-3163

Nearest miRNA

hsa-mir-101-1/Upstream/2354962; hsa-mir-1182/Downstream/1090104;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/100418, chr1-CpG: 62/Downstream/19406

Upstream sequence

GCAGCAGCCTGCCAGGATTAATTACACACCAGTGCTAACACATTTATCACCTCGCCGCTGATTGGAAAACCAATGACTTTTAATAATTCATATCTGTGGC

Downstream sequence

TCGGCACTCTGTGCCCTTGTGCAAAGACACAGAAACTCGCTTGTTTCCATAAGGAAAGCCCAGTGGCAGTGCCAGGAGGGGTGCCTTCAGCCCCTCCTGC