Basic Information
VIS ID
TVIS44021717
Fusion event
HTLV-1-SLC26A9-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
205916423/205947295 (Hg38)
End
205916423/205947295 (Hg38)
Orient
+
Location type
Intronic
Target gene
SLC26A9-AS1
Nearest miRNA
hsa-mir-101-1/Upstream/498897; hsa-mir-1182/Downstream/527508;
Nearest TSS
ENST00000473358/Upstream/3835; ENST00000604112/Downstream/45285;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/97232, chr1-CpG: 46/Downstream/170007
Nearby gene
SLC26A9(-3835) ;
Upstream sequence
AGCAAATACCTTAAGGCTAAAGACAGCAAAGTCTTCACCACCCTGCCCTGCAGTGGCAGGATCTGGCCTGGCCCTGCGCGGCTGCCAGTTTCATGAGTGC
Downstream sequence
TTGAGGACTGGTGGGACTGCAGAGGTACCCAAGGAGAAGCGAATCCTCACTTCTCTCCCCTGGGAAGCCCAGGGGCTCAAGTACCCCAGCTGTGAGTATC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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