Basic Information
VIS ID
TVIS44021736
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q42.2
Reference genome
GRCh37/hg19
Start
231263548/231127802 (Hg38)
End
231263548/231127802 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA1H
Nearest miRNA
hsa-mir-101-1/Upstream/107878; hsa-mir-1537/Downstream/2496350;
Nearest TSS
ENST00000473358/Upstream/87556; ENST00000449018/Downstream/34310;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/86539, chr1-CpG: 57/Downstream/33011
Nearby gene
TRIM67(+35126) ;
Upstream sequence
CTGTATCCCAGGCCCCCCAAGCAGCGAGCCCCGGTGCCCCCCACCTTTACCCCTCCTCCCCGGTGCCCAGGGCCCAGGAGGGAGATTGATGCGGGGTGCT
Downstream sequence
TATTAAAAAACATTGTAGccctctccctctccctctccctcaccctctccctctccctctccctctccctctttccacggtctccctctccctctcttcc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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