Basic Information
VIS ID
TVIS44021742
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q42.2
Reference genome
GRCh37/hg19
Start
234623359/234487613 (Hg38)
End
234623359/234487613 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA1H
Nearest miRNA
hsa-mir-101-1/Upstream/181074; hsa-mir-1537/Downstream/702421;
Nearest TSS
ENST00000473358/Upstream/8510; ENST00000429507/Downstream/44152;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/8387, chr1-CpG: 62/Downstream/112175
Nearby gene
TARBP1(-8510) ;
Upstream sequence
aaaccctcatttttctcaggatggcaacatactggcccttggccaatggcttatgtttaggcagcaaacaggacaagcctgttccctgcttctccaacca
Downstream sequence
tcattacaagtcgggcaatgggtgctctctgtgtcctagtcttggacaatgagacataagcagcagtctgctagggatgtgtctgggaaagcttttgctt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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