VISDB Viral Integration Site DataBase

VIS ID

TVIS44021744

Fusion event

HTLV-1-CHRM3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr1

Cytoband

q43

Reference genome

Start

End

239662061/239498761 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-296-3p ; hsa-mir-2467-3p ; hsa-mir-6878-5p ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-6760-5p ; hsa-mir-6873-5p ; hsa-mir-6856-5p ; hsa-mir-5197-3p ; hsa-mir-6758-5p ; hsa-mir-4311 ; hsa-mir-1277-5p ; hsa-mir-4776-3p ; hsa-mir-4659b-5p ; hsa-mir-4659a-5p ; hsa-mir-5590-5p ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-466 ; hsa-mir-5011-5p ; hsa-mir-4643 ; hsa-mir-4789-3p ; hsa-mir-137 ; hsa-mir-4446-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-670-5p ; hsa-mir-4445-5p ; hsa-mir-6766-3p ; hsa-mir-4782-3p ; hsa-mir-219a-5p ; hsa-mir-508-3p ; hsa-mir-339-5p ; hsa-mir-6079 ; hsa-mir-5186 ; hsa-mir-4522 ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-3973 ; hsa-mir-6888-5p ; hsa-mir-148a-5p ; hsa-mir-4428 ; hsa-mir-8075 ; hsa-mir-4728-3p

Nearest miRNA

hsa-mir-101-1/Upstream/2027570; hsa-mir-3123/Downstream/1633511;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/110722, chr1-CpG: 105/Downstream/498776

Nearby gene

CHRM3(+130312) ;

Upstream sequence

CATTACCTTACTATCATGAACTGGAATGTAGGTGTCTGGCAAAGCCTGATATACTTTTGTGTGTAAATTAATTTTTAAGACTTTTGTTTAAAATGTATCA

Downstream sequence

TTTCTCCCTTATTCTTTTACGGAACAGTTAGCTAATAAAACTTTAATAAATGAGTACTAGATTCTGGGCATTTGCAAGTTACTATGCGGTTATACATCTG