Basic Information
VIS ID
TVIS44021747
Fusion event
HTLV-1-RGS7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q43
Reference genome
GRCh37/hg19
Start
240988173/240824873 (Hg38)
End
240988173/240824873 (Hg38)
Orient
+
Location type
Intronic
Target gene
RGS7
Nearest miRNA
hsa-mir-101-1/Upstream/3353682; hsa-mir-3123/Downstream/307399;
Nearest TSS
ENST00000473358/Upstream/59316; ENST00000444330/Downstream/43922;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1264, chr1-CpG: 104/Downstream/531766
Upstream sequence
aaataaaggttaggtgggttatagggtgggaactaatacaatagaactggtgtccttttaagaagaggaagagaccccagagttggttgttttgttttgt
Downstream sequence
ttttctctctgtctctatgcacacacaggaaaagccactgaggacacgagaagaaggcagccatccccaagcaggaagagacactccacaggaactgaac
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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