VISDB Viral Integration Site DataBase

VIS ID

TVIS44021783

Fusion event

HTLV-1-AGO4 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr1

Cytoband

p34.3

Reference genome

Start

End

36320276/35854675 (Hg38)

Orient

+

Location type

UTR3

Target gene

miRNAs that regulate target gene

hsa-let-7a-5p ; hsa-mir-335-5p ; hsa-mir-155-5p ; hsa-mir-21-5p ; hsa-mir-484 ; hsa-mir-92a-3p ; hsa-mir-20a-5p ; hsa-mir-33a-3p ; hsa-mir-548at-5p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-545-3p ; hsa-mir-3121-3p ; hsa-mir-6079 ; hsa-mir-6828-5p ; hsa-mir-6838-5p ; hsa-mir-137 ; hsa-mir-6071 ; hsa-mir-192-3p ; hsa-mir-6828-3p ; hsa-mir-582-5p ; hsa-mir-671-5p ; hsa-mir-6782-3p ; hsa-mir-144-3p ; hsa-mir-101-3p ; hsa-mir-6507-5p ; hsa-mir-3692-5p ; hsa-mir-93-3p ; hsa-mir-129-5p ; hsa-mir-6832-3p ; hsa-mir-6834-3p ; hsa-mir-513b-3p ; hsa-mir-1976 ; hsa-mir-23a-5p ; hsa-mir-23b-5p ; hsa-mir-3653-5p ; hsa-mir-4279 ; hsa-mir-4438 ; hsa-mir-4722-3p ; hsa-mir-4740-3p ; hsa-mir-498 ; hsa-mir-5089-5p ; hsa-mir-5095 ; hsa-mir-5571-5p ; hsa-mir-619-5p ; hsa-mir-6504-3p ; hsa-mir-6506-5p ; hsa-mir-6727-3p ; hsa-mir-6747-3p ; hsa-mir-6778-3p ; hsa-mir-7151-3p

Nearest miRNA

hsa-mir-12136/Upstream/1184981; hsa-mir-101-1/Downstream/1306888;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/45815, chr1-CpG: 29/Downstream/28225

Upstream sequence

TTCTTATATATCATAATCTGGCAATTTCTGAAACCAGTCAGAAAAGACATATATTTCCATGCCTTTTTAAAGAATTATTTTTACCTGTTTTATATTCACA

Downstream sequence

GTTGGTGTCCTGTCACTTTGTTTTAAAATAAGCTAGAACCAGGATGCTTCCTTATTGGAAAGGCTTTGCCAGTCCTTAAGGTACAATGAGTGATGCTGCA