Basic Information
VIS ID
TVIS44021784
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p34.3
Reference genome
GRCh37/hg19
Start
39299465/38833793 (Hg38)
End
39299465/38833793 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12136/Upstream/744464; hsa-mir-101-1/Downstream/1920562;
Nearest TSS
ENST00000473358/Upstream/17814; ENST00000456813/Downstream/14281;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/14889, chr1-CpG: 72/Downstream/25350
Nearby gene
RRAGC(-4404) ;
Upstream sequence
GAGAAAGATAGGCCCTGTCTGGAGCCTCATTACCTGGAACACAAAGTTTGCATGCCAATTTGCATGGAGATAAGAGAGAGGCCATGGAAAGAAAGGAAGG
Downstream sequence
AATATTCACAATTTGCTAAAATGTGTGTGCCAGCACCTCTTTTTTAAAGAAAAGCAAAAAGAATATTGTAGAAAATTAATATTCCATTTCTCTAAGTCAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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