Basic Information
VIS ID
TVIS44021789
Fusion event
HTLV-1-SCMH1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p34.2
Reference genome
GRCh37/hg19
Start
41642726/41177054 (Hg38)
End
41642726/41177054 (Hg38)
Orient
-
Location type
Intronic
Target gene
SCMH1
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-532-3p ; hsa-mir-10b-5p ; hsa-let-7e-5p
Nearest miRNA
hsa-mir-12136/Upstream/419682; hsa-mir-101-1/Downstream/1994598;
Nearest TSS
ENST00000473358/Upstream/14037; ENST00000422305/Downstream/65056;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/159033, chr1-CpG: 155/Downstream/64231
Upstream sequence
gtgggtccctgacccccaagtagcctaactgggaggcaccccccagtaggggcagactgacacctcacacggccctctgagacaaaacttccagaggaac
Downstream sequence
gatcaggcagcaacatttgctgttcaccaatatccgctgttctgcagcctccgctgctgatacccaggcaaacagggtctggagtggacctccagcaaac
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate