Basic Information
VIS ID
TVIS44021794
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.32
Reference genome
GRCh37/hg19
Start
4573994/4513934 (Hg38)
End
4573994/4513934 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-12136/Upstream/953144; hsa-mir-101-1/Downstream/1348738;
Nearest TSS
ENST00000473358/Upstream/29559; ENST00000420522/Downstream/38211;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/352322, chr1-CpG: 317/Downstream/139995
Nearby gene
LINC01777(+89250) ;
Upstream sequence
AAGCTACGAAGTGGAGCCGGCAGACTTTCTATTACCCAGTCAATAAATGAGCTCTTTTCCCAGCAATATGGCTTTCTGTAGGGAGAGCAATAGCCAGTGT
Downstream sequence
GGGGAGGGAAACCAGGCTCGGCTCCAGGGAGGCTGCTGGAGGGAATTCTCCACGGCCCTGCTGCCTGGCATGAGGAGCTGGCCTCCTGGGCTGGGAAAGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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