VISDB Viral Integration Site DataBase

VIS ID

TVIS44021796

Fusion event

HTLV-1-AJAP1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr1

Cytoband

p36.32

Reference genome

Start

End

4828125/4768065 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-510-3p ; hsa-mir-5004-5p ; hsa-mir-494-3p ; hsa-mir-1197 ; hsa-mir-4538 ; hsa-mir-4453 ; hsa-mir-4661-5p ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-1277-5p ; hsa-mir-410-3p ; hsa-mir-3163 ; hsa-mir-4789-3p ; hsa-mir-548ay-3p ; hsa-mir-548at-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-335-3p ; hsa-mir-1279 ; hsa-mir-656-3p ; hsa-mir-5007-3p ; hsa-mir-548as-3p ; hsa-mir-6813-3p ; hsa-mir-4801 ; hsa-mir-4731-3p ; hsa-mir-4313 ; hsa-mir-7108-3p ; hsa-mir-3152-5p ; hsa-mir-6836-3p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-4641 ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6734-5p ; hsa-mir-4314 ; hsa-mir-4710 ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6878-5p ; hsa-mir-6738-5p ; hsa-mir-5194 ; hsa-mir-1914-3p ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-3192-5p ; hsa-mir-4646-5p ; hsa-mir-204-3p ; hsa-mir-2278 ; hsa-mir-6889-3p ; hsa-mir-3194-5p ; hsa-mir-4687-5p ; hsa-mir-6511a-3p ; hsa-mir-6511b-3p

Nearest miRNA

hsa-mir-12136/Upstream/1207275; hsa-mir-101-1/Downstream/1094607;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/55580, chr1-CpG: 17/Downstream/4226

Nearest cancer related gene

AJAP1(TSG, No orient, 0)

Upstream sequence

AGGGATTACCAGAGCTGGTAGACACTCCATTGTTGGTGGGATTAGGGGTGGTCCCTGTTGCATAACTTAGCTTTCAACTCATTAGCAAACCAACTTGGCA

Downstream sequence

GTCCCAGAGAAGGGACTTGCCCAGAGGTTTACAGCAGGTGCCACAGATGGGGCACAGGTTTATGGGAGGTCATTGGCCAGAACTGCAATGAATGCAGCAC