Basic Information
VIS ID
TVIS44021799
Fusion event
HTLV-1-AGBL4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p33
Reference genome
GRCh37/hg19
Start
49709138/49243466 (Hg38)
End
49709138/49243466 (Hg38)
Orient
-
Location type
Intronic
Target gene
AGBL4
Nearest miRNA
hsa-mir-12136/Upstream/4697914; hsa-mir-101-1/Downstream/1816371;
Nearest TSS
ENST00000473358/Upstream/197752; ENST00000420071/Downstream/13945;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/344225, chr1-CpG: 34/Downstream/780279
Upstream sequence
ATAAAATCTAATATTCTGAGAGCCCATAGCCAATTCCTTATCAAACCCTGGGAACATTTAGGATAATGGCTGCTGGGAGATAGGCTTGGGTGTAGGTAAC
Downstream sequence
TGACTCAAAGCATAAAAGGAAGTCCTAGACATAGAGCACCAAGGTGGAAGAAAAGATGTTCAAAATTCAACAGTAGCAAGGAGAATAACAATTATGATTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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