Basic Information
VIS ID
TVIS44021823
Fusion event
HTLV-1-SLC44A5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p31.1
Reference genome
GRCh37/hg19
Start
76184913/75719228 (Hg38)
End
76184913/75719228 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1L
Target gene
SLC44A5
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-101-1/Upstream/4651512; hsa-mir-11399/Downstream/1340915;
Nearest TSS
ENST00000473358/Upstream/108112; ENST00000473018/Downstream/4783;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/102548, chr1-CpG: 66/Downstream/5003
Nearby gene
ACADM(+5119) ;
Upstream sequence
gaagtttcctgacccgtggtaagtaatgaatgtcactttctaacaggatcagaaatctcaagatattttgagacctcaagaagagagaaatttgtacagg
Downstream sequence
tattataaatgcagtctaatggtgaatccttggctttgcttctggcgttgaggctttaaaacactggaataaaaaattctgatagttctagcaaagccaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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